Searchable abstracts of presentations at key conferences in endocrinology

ea0063p52 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Exome analysis of pituitary adenoma tissue derived cell cultures

Rovite Vita , Peculis Raitis , Mandrika Ilona , Petrovska Ramona , Megnis Kaspars , Balcere Inga , Konrade Ilze , Stukens Janis , Breiksa Austra , Nazarovs Jurijs , Pirags Valdis , Klovins Janis

Introduction: Pituitary adenomas (PA) are tumours of the anterior pituitary. Despite the benign nature these neoplasms cause increased mortality and morbidity. Clinically relevant PAs affect around 0.1% of population during their lifetime. Currently, there is no human PA cell culture models. Tissue cultures derived from PA surgery materials depending on harvesting conditions can form free floating aggregates called pituispheres (PS) or adherent mesenchymal stromal cells (MSC)....